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Tretinoin stimulates mitotic activity and increases follicular epithelial cells turnover, causing the extrusion of comedos. It also reduces hyperkeratinization that causes microcomedo lesions(acne). In the dermis blood vessel, tretinoin causes vasodilation, angiogenesis, and increased papillary dermal collagen synthesis, leading to reduced fine and course wrinkles. In turn, this reveals a smoother even tone skin.
Tretinoin is used in treatment of;
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