ACNESOL 0.05% W/W CREAM
COMPOSITION:Acnesol contais Tretinoin B.P 0.05% w/w as the active ingredient.
PHARMACOLOGY:Tretinoin
stimulates mitotic activity and increased turnover of follicular
epithelial cells causing extrusion of comedos. It also reduces
hperkeratinization that leads to microcomedo formation which is the
initial lesion in acne. In dermis blood vessel, vasodilation and
angiogenesis and increased papillary dermal collagen synthesis lead to
lessening of fine and course wrinkling smoother texture decrease in
hyperpigmentation.
PHARMACOKINETICS:Tretinoin is highly bound to
plasma roteins and undergoes metabolism in the liver. It’s excreted in
the bile and urine.
INDICATION:Acnesol is used for the treatment of the following
AcnePhotodamaged
skinHyperpigmentationADVERSE EFFECTSTretinoin is a skin irritant and
may cause peeling similar to that of sunburn. Sensitive inviduals may
experience oedema, buscemia and crusting of the skin.
DIRECTIONS:– Apply gently on the affected areas 1-2 times a day or as directed by a physician.
CONTRAINDICATIONS:Tretinoin
is teratogenic and is contraindicated in pregnancy, breastfeeding
mothers, on eczematous sunburn or branded skin.Do not apply it with
other topical treatment e.g. skin moisturizers
DRUG INTERACTION:Interacts with Tetracyclines and Carbamazepine
PRESENTATION:Available in 25g collapsible Aluminium tubes packed in unit boxes.
STORAGE:Do
not store above 30°C. Store in a dry place. Keep tightly closed.
Protect from direct sunlight. Keep all medicines out of reach of
children.Pernex AC 2.5% Gel is an anti-bacterial medicine that helps treat acne.
Acne appears as spots or pimples on your face, chest, or back. This
medicine works by killing acne-causing bacteria.
Pernex
AC 5% Gel may be used alone or with other acne treatments. You should
use it as advised by your doctor. Follow the instructions provided in
the product leaflet to get the most out of this medicine. Wash and dry
the affected area before medicine application. It is usually used once
or twice a day. Do not apply it to damaged or broken skin and avoid
contact with your mouth, eyes, and nose. It may take several weeks for
your symptoms to improve, keep using it as advised. Consult your doctor
after a month of regular use of this medicine, if your condition is not
improving.
Pernex
AC 2.5% Gel has some common side effects including itching, stinging,
peeling, and redness of the skin. They are not usually serious but tell
your doctor if they bother you or do not go away. You may need to apply a
smaller amount or use it less often. This medicine can make you more
sensitive to sunlight. While using it, try to avoid exposure to too much
sunlight. If this is unavoidable, apply the medicine in the evening. It
can also bleach hair and fabrics including clothes so be careful to
avoid contact with these.
It
is a safe medicine, but you should tell your doctor if you have other
skin conditions and if you are using any other medicines, especially
those applied to the skin. It may not be suitable if you have very
sensitive skin. Ask your doctor about using this medicine if you are
pregnant or breastfeeding.