tretinoin Tretinoin's Acnesol Acne Cream 25g & 0.05%

ACNESOL 0.05% W/W CREAM
COMPOSITION: Acnesol contains Tretinoin B.P 0.05% w/w as the active ingredient.
PHARMACOLOGY: Tretinoin stimulates mitotic activity and increases the turnover of follicular epithelial cells causing the extrusion of comedies. It also reduces hyperkeratinization which leads to micro-comedo formation which is the initial lesion in acne. In the dermis blood vessel, vasodilation and angiogenesis and increased papillary dermal collagen synthesis lead to the lessening of fine and course wrinkling smoother texture decrease in hyperpigmentation.
PHARMACOKINETICS: Tretinoin is highly bound to plasma proteins and undergoes metabolism in the liver. It’s excreted in the bile and urine.
INDICATION: Acnesol is used for the treatment of the following
Acne Photodamaged skin hyperpigmentation

ADVERSE EFFECTS Tretinoin is a skin irritant and may cause peeling similar to that of sunburn. Sensitive individuals may experience oedema, buscemia, and crusting of the skin.
DIRECTIONS:–    Apply gently on the affected areas 1-2 times a day or as directed by a physician.
CONTRAINDICATIONS:Tretinoin is teratogenic and is contraindicated in pregnancy, breastfeeding mothers, on eczematous sunburn or branded skin.Do not apply it with other topical treatment e.g. skin moisturizers
DRUG INTERACTION:Interacts with Tetracyclines and Carbamazepine
PRESENTATION:Available in 25g collapsible Aluminium tubes packed in unit boxes.